Variable information manipulation
It would be great to be able to add a feature to accept info in the condition, and be able to pass it to the settings.
For example, if someone has "Joe Smith's Birthday" in his calendar, and Locale reads that day in the calendar, it would be cool to be able to send out an SMS to Joe Smith for his Birthday.
Another example, if you receive a text from someone (say Joe Smith), you want to post a twitter response regarding "Joe Smith".
These are simple examples, but the usefulness just quadruples with this capability
I'd love to set and read variables- there was an addon that did this previously, but it's currently abandonware. I was able to make great use of this, but the addon is no longer functioning on Gingerbread.
I agree with janiskfp. This app is really about automating the "state" you want your phone to be in based on a time/location/etc.
What you're asking for is some sort of program that can activate scripts to run complex tasks... like a scheduler.
This sounds really cool, but if I were in charge of this project, I'd say it's out of scope. But that's just me, and I can be a, well, you know.